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Clotrimazole CAS no 23593-75-1

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Clotrimazole is a synthetic pyrrole antifungal drug, which has inhibitory effect on a variety of pathogenic fungi. It can also have a bactericidal effect when the concentration is high. Clotrimazole inhibits the biosynthesis of fungal ergosterol and other sterols by interfering with the activity of cytochrome P450; damages the fungal cell membrane and changes its permeability, causing the loss of important substances in the cell; it can also inhibit fungal triglycerides and phospholipids The biosynthesis; this product can still inhibit the activity of oxidation and peroxidase, causing excessive accumulation of peroxide in the cell, causing degeneration and necrosis of the fungal subcellular structure. Clotrimazole has a broad-spectrum antifungal activity. It has a good antibacterial effect against Epidermophyton, Trichophyton, Aspergillus, Pigmentation fungus, Cryptococcus and Candida, and has good antibacterial effect against Sporothrix schenckii and dermatitis blastomycetes. , Coccidioides spp., Histoplasma spp., etc. also have certain antibacterial activity. Clotrimazole has a good antibacterial effect against Candida, Cryptococcus, Aspergillus, Algae, Dermatophytes, etc. in vivo and in vitro. The curative effect of mycosis is similar to that of amphotericin B. It has a good effect on visceral pathogenic fungi such as Candida albicans, Cryptococcus neoformans, coccidioides and histoplasma, etc. It has a better effect on Candida albicans than nystatin. powerful. Fungi are not easy to develop resistance to this product.


Product Clotrimazole
CAS 23593-75-1
MF C22H17ClN2
MW 344.84


Product Categories : API Intermediates > Clotrimazole Intermediate

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shandong Bolode Biotechnology Co., Ltd. Is specializing in R&D, production and sales of various chemical products. Our dominant products are APIs, pharmaceutical intermediates, impurities and custom synthetic compounds. Here atached part of our catalogue for your reference. Our products are widely used in anti-cancer, anti-depression, anti-Alzheimer's, nutrition, anesthesia and analgesia, cardiovascular and other fields. Our products have been sold to many countries including USA, India, South Korea, South America, Japan and so on. We carry out quality control in accordance with ISO9001 and international standards such as USP, EP, JP, and CP to meet the needs customers. The product quality has been recognized by our customers from all over the world. We sincerely welcome inquiry from you.
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